KAIST Identifies a Molecular “Switch” That Activates Cell Growth Signaling, Suggesting a Potential Basis for Next-Generation Anticancer Therapy (IMAGE)

The Korea Advanced Institute of Science and Technology (KAIST)

KAIST Identifies a Molecular “Switch” That Activates Cell Growth Signaling, Suggesting a Potential Basis for Next-Generation Anticancer Therapy

Caption

Figure2. Schematic model of mTORC1 activation by LARS1 phosphorylation. Amino acid stimulation induces LARS1 phosphorylation, causing LARS1 to dissociate from the multi-tRNA synthetase complex (MSC) and activate mTORC1, ultimately promoting cell growth and proliferation.

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KAIST

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