The use of agrimoniin can alleviate hepatic and pulmonary angiogenesis and the fibrosis of liver tissue (IMAGE)
Caption
(A) Vascular casting of lungs and CT images in different groups. (B, C) Representative immunofluorescence images of liver and lung sections and comparison of the relative area of CD31 (red) in different groups and its graphical representation (n = 12 per group). (D, E) Representative VEGF and PLGF immunohistochemistry staining of liver and lung tissue from different groups and their graphical representation (n = 12 per group). (F) Concentration of growth factors (VEGF and PLGF) of liver and lung tissue in different groups (n = 8 per group). (G, H) Representative immunofluorescent staining of α-SMA in liver tissue from different groups and its graphical representation (n = 12 per group). Nuclei, DAPI (blue). Scale bar, 50 μm ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, and ∗∗∗∗p < 0.0001.
Credit
Ziyang Zeng, Zhiyong Yang, Yuhao Lei, Meiyu Zhou, Lin Chen, Yang Chen, Xianfeng Wu,Huiling Cao, Chunyong Yang, Xiaobo Wang, Karine Belguise, Yujie Li, Bin Yi
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