Mechanism diagram depicting that GBA-Ceramide-CTSD-BID-BAX signaling may be the key putative target pathway of artesunate in halting the progression of HCC, and Y313, E340, and N396 may serve as important binding sites of GBA protein with artesunate. (IMAGE)

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Mechanism diagram depicting that GBA-Ceramide-CTSD-BID-BAX signaling may be the key putative target pathway of artesunate in halting the progression of HCC, and Y313, E340, and N396 may serve as important binding sites of GBA protein with artesunate.

Caption

Mechanism diagram depicting that GBA-Ceramide-CTSD-BID-BAX signaling may be the key putative target pathway of artesunate in halting the progression of HCC, and Y313, E340, and N396 may serve as important binding sites of GBA protein with artesunate.

Credit

Xia Mao, Xiangying Yan, Yawen Chen, Bingbing Cai, Wenjia Chen, Ya Lin, Na Lin, Yanqiong Zhang

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