Figure 3 (IMAGE)

Tohoku University

Figure 3

Caption

Hematopoietic stem cells form a distinct gene regulatory network with aging. Among the genes characteristic of aged hematopoietic stem cells, Pbx1 contributes to reduced red blood cell production and relative enhancement of hematopoietic stem cell and megakaryocyte gene programs through suppression of Gata1 and activation of Group 1 genes.

Credit

Hiroshi Kobayashi et al.

Usage Restrictions

Reporters may freely use these materials in news coverage with appropriate credit information.

License

Original content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.