The diagram illustrates the difference between CRISPR-Cas9 and base editing. The study shows that the method used to disrupt DNA affects the mechanism by which it is repaired in early human embryos. (IMAGE)

Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences (IOCB Prague)

The diagram illustrates the difference between CRISPR-Cas9 and base editing. The study shows that the method used to disrupt DNA affects the mechanism by which it is repaired in early human embryos.

Caption

The diagram illustrates the difference between CRISPR-Cas9 and base editing. The study shows that the method used to disrupt DNA affects the mechanism by which it is repaired in early human embryos.
 

Credit

Adapted from Jeřábek et al., Nature, 2026

Usage Restrictions

For editorial use in connection with this press release only.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.