Internal benchmark evaluation and descriptive RNA quality audit of ChatBiobank (IMAGE)
Caption
(A) Benchmark strata, internal evidence-support and routing tiers, and blinded expert-review workflow. (B) Response-tier distribution by benchmark stratum. (C) Expert-rated outcomes cross-tabulated by internal response tier after restoration of the concealed labels; numbers within bars are counts. All 77 outputs assigned to Tier B met the professional-acceptability criterion (75 directly acceptable and 2 broadly acceptable). (D) Single-center descriptive RNA quality audit of 153 fresh-tissue biospecimens processed under the implemented local workflow, of which 150 met the prespecified local qualification criteria. The RNA audit was not designed to estimate the causal effect of ChatBiobank. KB, knowledge base; LLM, large language model; QC, quality control.
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Zhao Sun, Xuejiao Xia, Rui Deng, Chang Sun, Yunfei Wang, Zhuohang Li, Jiahui Li, Guanghui Li, Mingliang Yuan, Sanfei Peng, Xiangyang Yin, Zhiwei Zhao, Xinhua Dong, Qi Liu, Jing-Hua Yang, Zhen Yang, Yang Fu
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