Figure 2 (IMAGE)

Kanazawa University

Figure 2

Caption

Aire induces the expression of tissue-restricted antigens in medullary thymic epithelial cells, contributing to elimination of auto-reactive T cells. Medullary thymic epithelial cells express antigens that express in specific organs such as insulin, C-reactive protein, etc. Thus, it is possible to eliminate auto-reactive T cells, for example, those reactive with insulin.

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Kanazawa University

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