Antibody‑Selective Nanopore (IMAGE)

Technical University of Munich (TUM)

Antibody‑Selective Nanopore

Caption

This artist's rendering illustrates how single proteins are probed with an artificially engineered nanopore in a metallized solid-state membrane. A primary protein (dark red) anchored within the pore transiently binds an IgG antibody (light red) passing through the pore. The interaction time can be measured electrically (an exemplary current-vs.-time trace is shown at the top of the picture); this reveals the antibody's biological function. A carpet of self-assembled molecules (white hairs) is used to coat the gold pore walls, rendering the surface biologically inert.

Credit

Christof Hohmann, Excellence Cluster Nanosystems Initiative Munich (NIM), copyright NIM

Usage Restrictions

This image may be freely used, with copyright noted, in news coverage of NIM or participating scientists.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.