Entry Schematic (IMAGE)

Hokkaido University

Entry Schematic

Caption

The host enzyme Xkr8 is transported to the Ebola virus budding site along with viral glycoprotein(GP) and then incorporated to the viral envelope. Xkr8 flips PS from the inner layer to the outer layer of the envelope, exposing the phospholipids, which contribute to viral infection. VP40 is a major structural protein of the virus.

Credit

Nanbo A. et al., <i>PLoS Pathogens</i>, January 16, 2018

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