Salk Scientists Discover How to Prevent Undesirable Immune Attacks on Therapeutic Viruses (IMAGE)
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Salk Institute researchers discovered that inhibiting a protein called phospholipid scramblase 1 (PLSCR1) controls the infected cell's antiviral response and provides long-term protection from immune attack and excessive inflammation. Salk Institute researchers discovered that inhibiting the protein PLSCR1 controls the infected cell's antiviral response and provides long-term protection from immune attack and excessive inflammation. In the cortex of a mouse, adenovirus-transduced cells (red) appear among labeled microglia (dark blue) and subsets of neurons (light blue).
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Salk Institute
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