Cancer Gene Drives Vascular Disorder (2 of 2) (IMAGE)

American Association for the Advancement of Science (AAAS)

Cancer Gene Drives Vascular Disorder (2 of 2)

Caption

PIK3CA mutations impair blood vessel formation in mouse embryos (upper panels). Here, the mutations improved after treatment with a PI3Kα inhibitor (lower panels). This material relates to a paper that appeared in the 30 March 2016, issue of Science Translational Medicine, published by AAAS. The paper, by P. Castel at Memorial Sloan Kettering Cancer Center in New York, NY, and colleagues was titled, "Somatic PIK3CA mutations as a driver of sporadic venous malformations."

Credit

P. Castel <i>et al., Science Translational Medicine</i> (2016)

Usage Restrictions

Please cite the owner of the material when publishing. This material may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact <i>Science</i> for permission.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.