Protein IRE1 (IMAGE) University of California - San Francisco Caption The protein IRE1, shown here, mediates the unfolded protein response. Credit (Credit: UCSF/P.Walter) Usage Restrictions (Credit: UCSF/P.Walter) License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.