SARS-CoV-2 Virion, Phylogeny and Structural Effects of the D614G Mutation in the S Protein (IMAGE)

CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences

SARS-CoV-2 Virion, Phylogeny and Structural Effects of the D614G Mutation in the S Protein

Caption

To the left, this composite image depicts the three-dimensional structure of SARS-CoV-2 virion based on custom mesoscale 3D-model of SARS-CoV-2 with RCSB PDB 3D-surface data and experimental protein structures (PDB: 6VSB, 6VXX, 6VXY). To the top right, the three-dimensional structure of the viral S protein and a phylogenetic tree of international SARS-CoV-2 genomes is shown. To the bottom right, the predicted conformational change in the S protein structure caused by the D614G mutation is shown. The Illustration 3 was generated by data-driven vector-graphics extracted from Nextstrain.org, enabled by data from GISAID.org, world map-data from Openstreetmap.org and 3D elements rendered with Octane renderer for Unity3D.

Credit

Bobby Rajesh Malhotra / CeMM (Creative Commons license: CC BY-NC)

Usage Restrictions

Only to be used in the framework of the "Mutational Dynamics of SARS-CoV-2 in Austria" project with credit to CeMM.

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