Lung Disease Mouse Model with High Blood Uric Acid Levels (IMAGE)
Caption
Suppression of uricase (UOX), a uric acid-metabolizing enzyme, in a pulmonary pathological mouse model with elevated uric acid levels improved symptoms of lung disease in female mice only.
Credit
Dr. Tsuyoshi Shuto
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<p>Adapted from figures 2 & 3 of Fujikawa, H., Sakamoto, Y., Masuda, N., Oniki, K., Kamei, S., Nohara, H., ... Shuto, T. (2020). Higher Blood Uric Acid in Female Humans and Mice as a Protective Factor against Pathophysiological Decline of Lung Function. Antioxidants, 9(5), 387. doi:10.3390/antiox9050387 </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</a> which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The plots at the bottom of the image have been modified to fit the format of this press release. </p>
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