尿酸値の高い肺病態モデルマウスによる実験 (IMAGE) Kumamoto University Caption 肺病態モデルマウスの尿酸代謝酵素ウリカーゼ(UOX)の働きを抑制し、尿酸値を上昇させると、メスマウスのみ肺の病気の症状が改善する Credit Dr. Tsuyoshi Shuto Usage Restrictions <p>Adapted from figures 2 & 3 of Fujikawa, H., Sakamoto, Y., Masuda, N., Oniki, K., Kamei, S., Nohara, H., ... Shuto, T. (2020). Higher Blood Uric Acid in Female Humans and Mice as a Protective Factor against Pathophysiological Decline of Lung Function. Antioxidants, 9(5), 387. doi:10.3390/antiox9050387 </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">Creative Commons Attribution License</a> which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The plots at the bottom of the image have been modified to fit the format of this press release. </p> License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.