Relationship Between DNA methylation Rate of CpG3 and Left Amygdala Volume (IMAGE)

Kumamoto University

Relationship Between DNA methylation Rate of CpG3 and Left Amygdala Volume

Caption

Left amygdala volume and CpG3 methylation rate are inversely correlated in schizophrenic patients with hypoactive 5-HTTLPR. A significant correlation was found in schizophrenia (SZ) patients (solid line), but not found in controls (CT, dotted line).

Vertical axis: ratio of left amygdala volume to the whole brain (%), Horizontal axis: CpG3 methylation rate (%)

Credit

Professor Kazuya Iwamoto

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<p>Adapted from figure 3 of <a href="https://academic.oup.com/schizophreniabulletin/advance-article/doi/10.1093/schbul/sbaa075/5859552">Ikegame, T. et al, 2020</a>. </p> <p>This image is made available under Oxford University Press <a href="https://academic.oup.com/journals/pages/access_purchase/rights_and_permissions/publication_rights">"Rights retained by ALL Oxford Journal authors"</a>. Any further distribution of this work must follow OUP's terms of reuse. </p>

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