Synthesis of Biomolecules (IMAGE) The Journal of Visualized Experiments Caption After a week of sparking in a Miller-Urey experiment, the contents within the reactant flask become visibly transformed. Miller-Urey's groundbreaking work is considered to be the first deliberate, efficient synthesis of biomolecules under simulated primitive Earth conditions. Credit <i>JoVE—The Journal of Visualized Experiments</i> Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.