Solving the Structural Mysteries of a Calcium-Binding Protein (1 of 1) (VIDEO)

American Association for the Advancement of Science (AAAS)

Caption

A simulation of how calcium ions (red balls) preferentially bind to a structure called the canonical EF hand (red) in the STIM1 calcium-binding protein. This material relates to a paper that appeared in the Nov. 19, 2019, issue of Science Signaling, published by AAAS. The paper, by R. Schober at Johannes Kepler University Linz in Linz, Austria; and colleagues was titled, "Sequential activation of STIM1 links Ca²⁺ with luminal domain unfolding."

Credit

R. Schober <i>et al., Science Signaling</i> (2019)

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