video: A simulation of how calcium ions (red balls) preferentially bind to a structure called the canonical EF hand (red) in the STIM1 calcium-binding protein. This material relates to a paper that appeared in the Nov. 19, 2019, issue of Science Signaling, published by AAAS. The paper, by R. Schober at Johannes Kepler University Linz in Linz, Austria; and colleagues was titled, "Sequential activation of STIM1 links Ca2+ with luminal domain unfolding." view more
Credit: R. Schober <i>et al., Science Signaling</i> (2019)