The Role of Il1b and Macrophages During Fin Regeneration (IMAGE)

Tokyo Institute of Technology

The Role of Il1b and Macrophages During Fin Regeneration

Caption

After tissue injury (A), epithelial cells secrete Il1b which activates regeneration-induced genes and promotes proliferation of surrounding cells (B). Macrophages attenuate Il1b expression, preventing chronic inflammation (C); otherwise, regenerative cells die by apoptosis induced by Il1b excess (D).

Credit

Tokyo Institute of Technology

Usage Restrictions

None

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.