High-resolution 3D structure of SNX27 (IMAGE)

Salk Institute

High-resolution 3D structure of SNX27

Caption

A high-resolution 3D structure of SNX27 PDZ domain bound to GIRK C-terminal tail. Surface rendering of the electrostatic potential (blue corresponds to positive charges) of SNX27 PDZ and the six-amino acid-“zip code” it recognizes. The red circle shows the newly identified 2nd site pocket and negatively charged GIRK3 residue.

Credit

Image: Courtesy of Bartosz Balana and Paul Slesinger, Salk Institute for Biological Studies

Usage Restrictions

News media reproduction to illustrate this story permitted with proper attribution as provided above. For one time use only.

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.