Combined Recognition Strategy Allows CAR T Cells to Kill Solid Tumors in Mice and Avoid Side Effects (1 of 3) (VIDEO)

American Association for the Advancement of Science (AAAS)

Caption

SynNotch CAR T cells targeting and killing EGFRvIII? tumor cells (blue) in the presence of priming cells (orange). This material relates to a paper that appeared in the Apr. 28, 2021, issue of Science Translational Medicine, published by AAAS. The paper, by J.H. Choe at University of California, San Francisco in San Francisco, CA; and colleagues was titled, "SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma."

Credit

J.H. Choe <i>et al., Science Translational Medicine</i> (2021)

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