Cryo-MOST Imaging System (IMAGE)

Optica

Cryo-MOST Imaging System

Caption

The cryo-MOST imaging system allows whole-brain mapping of senile plaques in the mouse brain. The system cools the sample by keeping it immersed in liquid nitrogen to enhance fluorescence from senile plaques. For whole-brain imaging, the XYZ stages move the sample to automatically alternate between imaging and the miller machine that removes a layer of the tissue each time the surface is imaged.

Credit

Jing Yuan, Huazhong University of Science and Technology

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