4 Versions of a Gene's Message (IMAGE) Cold Spring Harbor Laboratory Caption A gene can give rise to multiple RNA messages, each resulting in a different variant, or isoform. Here are the 4 messenger RNA isoforms generated by the human AFMID gene. From top: two isoforms normally found in adult cells. Lower two variants are missing some of the 11 segements, called exons, in the main isoform; these give rise to truncated proteins associated with liver cancer. Credit Krainer Lab, CSHL Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.