Molecular Structure of the Super-photostable Fluorescent Labeling Agent, PhoxBright430 (PB430) (IMAGE)

Institute of Transformative Bio-Molecules (ITbM), Nagoya University

Molecular Structure of the Super-photostable Fluorescent Labeling Agent, PhoxBright430 (PB430)

Caption

PB430 consists of a fully ring-fused π-conjugated skeleton with an electron accepting phosphole P-oxide unit, which is responsible for its high photostability. The carboxylic acid of the molecule can be converted to the N-hydroxylsuccinimidyl (NHS) ester, which allows conjugation to biomolecules. Sulfonate groups ensure high solubility of the molecule in water.

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ITbM, Nagoya University

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