Suppression of the mRNA Turn-Over Leads to Necroptosis (IMAGE)

Okinawa Institute of Science and Technology (OIST) Graduate University

Suppression of the mRNA Turn-Over Leads to Necroptosis

Caption

Intact CCR4-NOT complex (on the left) suppresses mRNAs encoding RIPK1 and RIPK3 proteins, thereby aiding cell survival. CNOT3-depleted cells (on the right) reveal increased expression and stability of these mRNAs.

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OIST

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