Tumor-Derived Organoids (IMAGE)
Caption
Tumor-derived organoids were transplanted to mouse spleen (top), and p53 status of the liver metastasized tumor cells were analyzed b PCR (middle). Notably, most metastasized tumor cells lost wild-type p53, suggesting that loss of p53 with GOF mutant p53 accelerates liver metastasis.
Credit
Kanazawa University
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