ISRIB (IMAGE) Howard Hughes Medical Institute Caption Using cryo-electron microscopy, researchers have revealed atomic-level details of the interactions between ISRIB, a brain-boosting experimental drug, (propeller-shaped molecule, center), and its target protein, eIF2B. Credit J. Tsai et al./<i>Science</i> 2018 Usage Restrictions Must use with credit. License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.