Peptide Fibrils in Water (IMAGE)

National Institute of Standards and Technology (NIST)

Peptide Fibrils in Water

Caption

Appears in: The Shape in Water: First Nanometer-Scale Measurements of the Folded Structure of Biomolecules in Liquids. Atomic force microscope image showing topography (top) and PTIR absorption image indicating composition and conformation (bottom) of a diphenylalanine peptide fibril in water. Additional data, recording the spectrum of infrared radiation absorbed by the peptide fibrils, provides information on their folding pattern. The PTIR spectrum indicated, for example, that diphenylalanine assumes a pure anti-parallel β-sheet conformation.

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NIST

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