Polycystic Kidney Disease (IMAGE) Children's National Hospital Caption Polycystic kidney disease is a genetic disorder characterized by clusters of fluid-filled sacs (cysts) multiplying and interfering with the kidneys' ability to filter waste from the blood. Credit Mohammed Haneefa Nizamudeen; istock Usage Restrictions Please credit Mohammed Haneefa Nizamudeen; istock License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.