Position and combination of DNA-motifs decide the gene expression (IMAGE)

Chalmers University of Technology

Position and combination of DNA-motifs decide the gene expression

Caption

Using the AI approaches, the researchers uncover regulatory rules that define which DNA motifs must be present together on a gene and at which locations to regulate gene expression across a range of levels from low to high. Previous studies focus just on single motifs in single regulatory regions (marked 'original motif'), whereas here they expand the view across multiple regulatory regions and multiple motifs (marked 'additional motifs').

Credit

Jan Zrimec/Chalmers University of Technology

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