Digital Breast Tomosynthesis Improves Invasive Cancer Detection (2 of 2) (IMAGE)
Caption
Images show asymptomatic false-negative cancer in a 49-year-old white woman with a family history of breast cancer (sister at 44 years of age; paternal aunt at 44 years and contralateral cancer at 80 years) and prior biopsy history of lobular intraepithelial neoplasia who presented for high-risk screening MRI 246 days after a benign screening mammogram. (a) Negative screening right digital breast tomosynthesis mediolateral oblique and craniocaudal mammograms. (b) Axial contrast-enhanced T1 subtraction MRI scan shows an enhancing irregular mass in the right breast (arrow). (c) Postcontrast T1 subtraction sagittal MRI scan enables confirmation of an enhancing irregular mass in the upper outer quadrant of the right breast, with additional smaller mass and nonmass enhancement. Subsequent MRI-guided biopsy yielded infiltrating mammary cancer with tubulolobular features and estrogen receptor- and progesterone receptor-positive and human epidermal growth factor receptor 2-negative invasive ductal carcinoma.
Credit
Radiological Society of North America
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