Directed Evolution Approach (IMAGE)

Ecole Polytechnique Fédérale de Lausanne

Directed Evolution Approach

Caption

The starting complex is a DNA-SWCNT with a dim optical signal. This is evolved through directed evolution: (1) random mutation of the DNA sequence; (2) wrapping of the SWCNTs with the DNA and screening of the complex's optical signal; (3) selection of the DNA-SWCNT complexes exhibiting an improved optical signal. After several cycles of evolution, we can evolve DNA-SWCNT complexes that show enhanced optical behavior.

Credit

Benjamin Lambert (EPFL)

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