bio-ADM / Endothelial Function Biomarker (IMAGE)

sphingotec GmbH

bio-ADM / Endothelial Function Biomarker

Caption

Research has identified bioactive Adrenomedullin (measurable with assay IB10 sphingotec® bio-ADM®) as a controlling hormone of the endothelial barrier, the interior wall protecting the blood vessels. In certain conditions such as septic shock, cardiogenic shock or acute heart failure, the endothelial barrier becomes leaky, and additional bio-ADM® is produced to re-seal the barrier. However, bio-ADM® has a second function. It also expands the blood vessels, resulting in a dangerous blood pressure drop, which leads to shock and may ultimately escalate into multiple organ failure.

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SphingoTec GmbH

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