Nanophotonic Label-Free Biosensor for Chemically Distinguishing Multiple Analytes in Biological Samp (IMAGE)

Ecole Polytechnique Fédérale de Lausanne

Nanophotonic Label-Free Biosensor for Chemically Distinguishing Multiple Analytes in Biological Samp

Caption

(a) Multi-resonant mid-IR nanoantennas are leveraged to enhance the vibrational absorption signals associated with biomimetic lipid membrane formation, polypeptide/membrane interaction, and vesicular cargo release on the sensor surface. (b) Antenna resonance positions are engineered to simultaneously overlap with the vibrational signatures of both the amide I, II and the CH2, CH3 absorption bands, allowing for the simultaneous enhancement and detection of lipid- and protein-induced absorption changes.

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EPFL

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