Validation of motor function recovery and delta wave correlation and safety (IMAGE)
Caption
(A) Normalized beam walking speed shows that the LIFU group is significantly faster at subacute I and chronic phase. (denotes p < 0.05). (B) Correlation between balance beam walking speed and pdBSI in the LIFU group. (C) Midsagittal sections of cerebellum vermis stained with H&E. Each image shows representative cerebellum morphology of both normal (top) and LIFU stimulated mouse (bottom). Arrowheads mark Purkinje cell soma. No evidence of hemorrhage, tissue damage, and Purkinje cell loss was found in the sonicated tissues. (ML, Molecular layer; PCL, Purkinje cell layer; IGL, Internal granular layer; WM, White matter. Scale bars: 50 μm).
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Korea Institue of Science and Technology(KIST)
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