Mouse embryonic stem cells (IMAGE)

Centro Nacional de Investigaciones Oncológicas (CNIO)

Mouse embryonic stem cells

Caption

Two mouse embryonic stem cells in which two Polycomb regions from different chromosomes (HoxC, green; HoxD, red) appear next to each other (arrows). Cohesin-SA2 promotes this type of contacts between distant Polycomb regions, while cohesin-SA1 does the opposite.

Credit

Molecular Cytogenetics Unit. CNIO

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