Catalytic dearomative defunctionalization of Arenes (IMAGE)

Waseda University

Catalytic dearomative defunctionalization of Arenes

Caption

2D bromoarenes were reacted with diazo compounds and malonates in the presence of a palladium catalyst to yield highly functionalized 3D alicyclic compounds, which are extremely prominent in pharmaceuticals.

Credit

Junichiro Yamaguchi

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