When the Mesh Breaks 2 of 2 (VIDEO)

American Society for Cell Biology

Caption

Two different RNP droplets, nucleoli (red) and histone locus bodies (HLBs) (green), are suspended in the nucleus of the frog oocyte by a nuclear actin mesh. Disrupt the mesh and these nuclear bodies immediately start falling, the nucleoli sinking faster because of their larger size and higher density. The grid size is 50 microns.

Credit

Videos courtesy of Marina Feric & Cliff Brangwynne, Princeton University

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