Modified and Natural Invagination (IMAGE) European Molecular Biology Laboratory Caption This is a top view of modified and natural invagination. While the left tissue is modified with optogenetics and does not invaginate, the right tissue folds towards the embryo's inside and creates a pouch. Credit IMAGE: Daniel Krueger/EMBL Usage Restrictions None License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.