Changes in protein expression levels related to drug detoxification and elimination caused by the condition of intestinal flora. (IMAGE)

Kumamoto University

Changes in protein expression levels related to drug detoxification and elimination caused by the condition of intestinal flora.

Caption

When the intestinal flora changes, as happens when antibiotic drugs are administered, drug-metabolizing enzymes and drug-transporting proteins are greatly reduced leading to a decreased ability to detoxify and eliminate the drugs from the system and can lead to an increase of side effects. DOI: 10.1021/acs.molpharmaceut.6b00259

Credit

Dr. Sumio Ohtsuki

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