XPG Catalytic Core (IMAGE) DOE/Lawrence Berkeley National Laboratory Caption Mutations in XPG can lead to two diseases, xeroderma pigmentosum (gray spheres) and Cockaynes syndrome (magenta spheres) and were mapped onto the XPG structure in this study to understand the direct impact on protein integrity. Credit Susan Tsutakawa Usage Restrictions Use credit License Licensed content Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.