Some Cancer Drugs in Clinical Trials Don't Work by Hitting Their Targets (2 of 2) (VIDEO)

American Association for the Advancement of Science (AAAS)

Caption

Ten experimental cancer drugs kill tumors in ways that are entirely different than how clinicians thought they did, revealing important insights for precision therapy. CSHL Fellow Jason Sheltzer investigates alongside Ann Lin and Christopher J. Giuliano. This material relates to a paper that appeared in the Sep. 11, 2019, issue of Science Translational Medicine, published by AAAS. The paper, by A. Lin at Cold Spring Harbor Laboratory in Cold Spring Harbor, NY; and colleagues was titled, "Off-target toxicity is a common mechanism of action of cancer drugs undergoing clinical trials."

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[Credit: CSHL Public Affairs]

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