Image (IMAGE)

Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)

Image

Caption

Confocal microscopy projection image of a mouse heart in which a multispectral genetic mosaic was induced in coronary vessels. This novel genetic and imaging technology was used to label and fate map individual coronary endothelial cells containing distinct genetic mutations. These mutations either impair or promote cell-cycle progression, determining the arterial or venous fate of endothelial cells. To form arteries, cells need to lower their metabolism and exit the cell-cycle (G0).

Credit

CNIC

Usage Restrictions

Use wiht credit

License

Licensed content

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.