Tumor Antigens Help Explain Varied Reactions to Immunotherapy (2 of 5) (IMAGE)

American Association for the Advancement of Science (AAAS)

Tumor Antigens Help Explain Varied Reactions to Immunotherapy (2 of 5)

Caption

Even complex regions of evolved tumors bear hallmarks of their origins, shown here in yellow. This material relates to a paper that appeared in the March 3, 2016, online issue of Science, published by AAAS. The paper, by N. McGranahan at The Francis Crick Institute in London, UK, and colleagues was titled, 'Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.'

Credit

Cancer Research UK, produced by Phospho Biomedical Animation

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