image: Even complex regions of evolved tumors bear hallmarks of their origins, shown here in yellow. This material relates to a paper that appeared in the March 3, 2016, online issue of Science, published by AAAS. The paper, by N. McGranahan at The Francis Crick Institute in London, UK, and colleagues was titled, 'Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade.' view more
Credit: Cancer Research UK, produced by Phospho Biomedical Animation