Figure 2. CSF1R Inhibition Rapidly Depleted all Retinal Microglia (IMAGE)

Chinese Academy of Sciences Headquarters

Figure 2. CSF1R Inhibition Rapidly Depleted all Retinal Microglia

Caption

This is (a) Scheme of PLX5622 administration and time points for observation. (b) Spatial distributions of retinal microglia show that cell numbers were reduced after PLX5622 administration. (c) Scheme of microglial repopulation and time points for examination. (d) Spatial distributions of retinal microglia show that microglia repopulated the whole retina after removal of PLX5622. Each green dot represents a microglial cell. S: superior; I: inferior; N: nasal; T: temporal; PLX5622: PLX5622 (a CSF1R inhibitor)-formulated diet. CD: control diet.

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Bo Peng

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