Senescent cancer-associated fibroblasts (CAFs) in ascites of gastric cancer patients (IMAGE)

Kumamoto University

Senescent cancer-associated fibroblasts (CAFs) in ascites of gastric cancer patients

Caption

<p>A: Researchers investigated the cellular senescence and secretion of senescence-related proteins in the ascites of gastric cancer patients and found that CAFs secrete more senescence-related proteins and promote cancer progression than other (cancer and blood) cells. </p> <p>B: Senescent CAFs secrete more senescence-related proteins than non-aging CAFs. </p>

Credit

Dr. Takatsugu Ishimoto

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<p>(A) and (B) are adapted from Fig. 4(E and F, right) of <a href="https://www.sciencedirect.com/science/article/pii/S2211124721000929">Yasuda T. et.al., Cell Reports, 2021</a>. </p> <p>This image is made available under the terms of <a href="https://creativecommons.org/licenses/by/4.0/">CC by 4.0</a>. Any further distribution of this work must follow the terms of this license. </p>

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