Mutation Favored by Natural Selection Identified by iSAFE (IMAGE)

University of California - San Diego

Mutation Favored by Natural Selection Identified by iSAFE

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The algorithm also identified a host of previously unknown mutations, including five that involve genes related to pigmentation. In these cases, iSAFE identified identical mutations in multiple non-African populations. This suggests an early response to the onset of selection as humans migrated out of Africa. Red: ancestral-blue: derived

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University of California San Diego

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