Chromatin Integration Labeling Sequencing (IMAGE)

Tokyo Institute of Technology

Chromatin Integration Labeling Sequencing

Caption

Histone modifications or transcription factors are labeled with ChIL probe in cell nuclei (right), and the genomic sequence proximal to the probe is amplified for large scale sequencing analysis (left). The profiles observed in 100 cells are similar to those using more than 1,000 cells.

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Nature Cell Biology

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